Xylometazoline

• Xylometazoline is typically administered as a nasal spray or drops and provides quick relief, usually within minutes.
• It can lead to rebound congestion, a condition where nasal passages become more congested once the medication is stopped.

Chemical Formula:

• C₁₆H₂₄N₂

Basic Structural Features:

• Another imidazoline derivative, structurally related to oxymetazoline.
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Mechanism of Action:

• Primarily α1 agonist → vasoconstriction of nasal mucosal blood vessels.

Side Effects of Xylometazoline:

• Rebound congestion with prolonged use, dryness, potential for systemic effects if overused.

Uses of Xylometazoline:

• Over-the-counter nasal decongestant sprays.

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