Zolpidem (non-benzodiazepine hypnotic)

  • Zolpidem (non-benzodiazepine hypnotic) treats insomnia by inducing fast sleep with minimal hangover.
  • Zolpidem (non-benzodiazepine hypnotic) enhances GABA action, offering short-acting sedative effects.

Chemical Formula:

  • C₁₉H₂₁N₃O

Chemical Structure of Zolpidem (non-benzodiazepine hypnotic)

Mechanism of Zolpidem (non-benzodiazepine hypnotic):

  • Selective binding to BZ1 (α1 subunit) of GABA-A receptor
  • Induces sleep with minimal muscle relaxant or anticonvulsant activity
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Uses of Zolpidem (non-benzodiazepine hypnotic):

  • Insomnia (short-term use)

Side Effects:

  • Nightmares
  • Sleepwalking
  • Dizziness
  • Next-day drowsiness (esp. in high doses)

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