Casein

  • Casein is a milk protein used in food, pharma, and nutraceuticals for its high nutritional and functional value.
  • Casein supports muscle growth, slow protein release, and is vital in dietary supplements and drug formulations.

General Information

  • Synonyms: Milk Protein
  • Biological Source:
    • Obtained from cow’s milk (80 percent of total milk protein).
  • Family: Not applicable (Derived from milk).
  • Geographical Source:
    • Found in India, USA, New Zealand, Australia, Germany.
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Macroscopical Characters of Casein

  • Color: White or cream-colored.
  • Texture: Fine powder or curd.
  • Taste: Bland.
  • Odor: Odorless.

Chemical Constituents

  • Proteins: Caseins contains essential amino acids (Leucine, Lysine).
  • Calcium & Phosphate: Important for bone health.
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Preparation

  1. Milk is acidified using lactic acid or rennet.
  2. Curd is separated, washed, and dried.
  3. Ground into powder for pharmaceutical use.

Evaluation

  • Solubility: Insoluble in water, dissolves in alkali.
  • Purity Tests:
    • Xanthoproteic Test → Yellow color indicates proteins.
    • Precipitation Test → Caseins precipitates in acid.
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Preservation & Storage

  • Stored in cool, dry conditions to prevent microbial growth.

Therapeutic Uses

  • Used in dietary supplements (protein powder for muscle growth).
  • Milk-derived casein is used in infant formulas.
  • Source of calcium for bone health.

Commercial Utility

  • Used in food industry (cheese, protein bars).
  • Used in paints and adhesives (casein-based glues).
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