Propoxycaine

Propoxycaine is an ester-type local anesthetic used with procaine for dental procedures by blocking nerve conduction.

Structure of Propoxycaine

  • It is an amino benzoic acid derivative with a propoxyethyl ester group, enhancing its solubility and anesthetic efficacy.
  • Chemical Formula: C₁₂H₂₉N₃O₂

Structure of Propoxycaine

Mode of Action

  • Sodium Channel Inhibition: Blocks voltage-gated sodium channels, preventing nerve impulse transmission.
  • Membrane Stabilization: Decreases nerve excitability by altering ion flow.
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Uses

  • Local Anesthesia: Employed in minor surgical procedures, dental applications, and cosmetic treatments.
  • Topical Preparations: Applied to skin and mucous membranes for temporary numbing.
  • Infiltration Anesthesia: Injected to provide localized numbness during medical interventions.

Side Effects of Propoxycaine

  • Local Irritation: Redness, swelling, or discomfort at the application site.
  • Systemic Toxicity: Potential CNS and cardiovascular effects with excessive use.

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