Thiophene is a five-membered aromatic heterocyclic compound with one sulfur atom, important in drugs, dyes, and conducting materials.
Chemical Formula of Thiophene:
- C₄H₄S
Physical Properties of Thiophene:
| Property | Value |
| Appearance | Colorless to pale yellow liquid |
| Odor | Benzene-like |
| Boiling Point | 84 °C |
| Melting Point | -38 °C |
| Solubility | Soluble in organic solvents; poorly in water |
| Density | ~1.05 g/cm³ |
Medicinal Uses:
- Thiophene ring is a bioisostere of benzene in medicinal chemistry.
- Found in:
- Antidepressants (e.g., Tianeptine)
- Anti-inflammatory drugs
- Antipsychotics (e.g., Olanzapine)
- Antihypertensive agents
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