Type 2 Diabetes Introduction
- Type 2 diabetes, previously known as adult-onset diabetes or non-insulin-dependent diabetes.
- The most common form of diabetes.
- Characterized by insulin resistance and relative insulin deficiency.
Causes of Type 2 diabetes
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Genetic Factors
- Family history increases risk.
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Lifestyle Factors
- Obesity, physical inactivity, poor diet, and aging.
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Metabolic Syndrome
- A cluster of conditions: high blood pressure, high blood sugar, abnormal cholesterol levels, and excess body fat around the waist.
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Symptoms
- Increased thirst and urination
- Increased hunger
- Fatigue
- Blurred vision
- Slow-healing sores or frequent infections
- Acanthosis Nigricans
- Areas of darkened skin, often in the armpits and neck.
Pathophysiology of Type 2 Diabetes:

- Insulin Resistance: Cells in the body become less responsive to insulin.
- Beta Cell Dysfunction: The pancreas produces less insulin over time.
- Hyperglycemia: Persistently high blood glucose levels due to the combination of insulin resistance and reduced insulin production.
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Diagnosis
- Fasting Blood Glucose Test: Elevated glucose levels after fasting.
- A1C Test: Measures average blood glucose levels over the past 2-3 months.
- Oral Glucose Tolerance Test (OGTT): Elevated blood glucose levels after consuming a glucose drink.
Treatment
- Lifestyle Changes: Healthy eating, regular physical activity, and weight loss.
- Medications: Oral medications (e.g., metformin) and sometimes insulin or other injectable medications.
- Blood Glucose Monitoring: Regular monitoring to manage blood glucose levels.
- Education and Support: Diabetes education programs for self-management skills.
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