Anti-Anginal

• Angina Pectoris
• Anti-Anginal Drugs

• Amyl Nitrite
• Nitroglycerin
• Pentaerythritol Tetranitrate
• Isosorbide Dinitrite
• Dipyridamole

Various Calcium Channel Blockers

• Verapamil
• Bepridil Hydrochloride
• Diltiazem Hydrochloride
• Nifedipine
• Amlodipine
• Felodipine
• Nicardipine
• Nimodipine

• Diuretics: Overview and Classification

Various Carbonic Anhydrase Inhibitors

• Acetazolamide
• Methazolamide
• Dichlorphenamide

Various Thiazides

• Chlorthiazide
• Hydrochlorothiazide
• Hydroflumethiazide
• Cyclothiazide

Various Loop Diuretics

• Furosemide
• Bumetanide
• Ethacrynic Acid

Various Potassium-Sparing Diuretics

• Spironolactone
• Triamterene
• Amiloride

Various Osmotic Diuretics

• Mannitol

• Hypertension
• Anti-Hypertensive Agents

Various Beta-Blockers

• Timolol

Various ACE Inhibitors

• Captopril
• Lisinopril
• Enalapril
• Benazepril Hydrochloride
• Quinapril Hydrochloride

Various Alpha-2 Agonists

• Methyldopate Hydrochloride
• Clonidine Hydrochloride

Various Sympatholytics

• Guanethidine Monosulphate
• Guanabenz Acetate
• Reserpine

Direct Vasodilators

• Sodium Nitroprusside
• Diazoxide
• Minoxidil
• Hydralazine Hydrochloride
• Reserpine

Other Units of Medicinal Chemistry II

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Medicinal Chemistry II

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Other Subjects of B Pharmacy 5th Semester

Unit II Summary: Anti-Anginal, Diuretics, and Anti-Hypertensives

This unit explains medicines used in heart-related problems. To begin with, anti-anginal drugs help reduce chest pain. For example, vasodilators like Nitroglycerin*, Isosorbide dinitrate*, and Dipyridamole increase blood flow to the heart. Similarly, calcium channel blockers such as Amlodipine, Verapamil, and Diltiazem relax the heart muscles and lower blood pressure.

Next, let’s look at diuretics, which help remove extra water and salt from the body. There are different types. Firstly, carbonic anhydrase inhibitors like Acetazolamide* reduce fluid in the body. Secondly, thiazide diuretics such as Hydrochlorothiazide lower blood pressure effectively. Thirdly, loop diuretics like Furosemide* act fast and are used in emergencies. In contrast, potassium-sparing diuretics like Spironolactone help keep potassium in the body. Finally, osmotic diuretics like Mannitol are used to treat brain swelling.

After that, the unit discusses anti-hypertensive drugs. These are used to manage high blood pressure. Examples include beta-blockers like Timolol, ACE inhibitors like Captopril and Enalapril, and central-acting drugs such as Clonidine* and Methyldopa. Furthermore, vasodilators like Minoxidil and Sodium nitroprusside help relax blood vessels.

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