Anti-Anginal & Diuretics Notes [U-2]
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Anti-Anginal
Various vasodilators drugs
Various Calcium Channel Blockers
- Verapamil
- Bepridil Hydrochloride
- Diltiazem Hydrochloride
- Nifedipine
- Amlodipine
- Felodipine
- Nicardipine
- Nimodipine
Diuretics
Various Carbonic Anhydrase Inhibitors
Various Thiazides
Various Loop Diuretics
Various Potassium-Sparing Diuretics
Various Osmotic Diuretics
Anti-Hypertensive Agents
Various Beta-Blockers
Various ACE Inhibitors
Various Alpha-2 Agonists
Various Sympatholytics
Direct Vasodilators
- Sodium Nitroprusside
- Diazoxide
- Minoxidil
- Hydralazine Hydrochloride
Other Units of Medicinal Chemistry II
Medicinal Chemistry II
Other Subjects of B Pharmacy 5th Semester
Topic wise notes of:
Industrial Pharmacy I
- Pre-Formulation Studies
- Tablets & Liquid Orals
- Hard & Soft Gelatin Capsules, Pellets
- Parenteral Products & Ophthalmic preparations
- Cosmetic, Pharmaceutical Aerosols & Packaging Materials
Topic wise notes of:
Pharmacognosy & Phytochemistry II
- Metabolic Pathways and Biogenesis of Secondary Metabolites
- Secondary Metabolites: Classification, Sources and Therapeutic Applications
- Isolation, Identification of Key Phytoconstituents
- Industrial Production of Essential Phytoconstituents
- Modern Extraction Techniques
Topic wise notes of:
Pharmacology II
- Pharmacology of Drugs
- Drugs on Cardiovascular & Urinary System
- Autocoids and Related Drugs
- Pharmacology of Drugs Acting on Endocrine System
- Bioassay
Topic wise notes of:
Pharmaceutical Jurisprudence
- Drugs and Cosmetics Act, 1940 and its rules 1945
- Regulatory Framework and Administration under Act, 1940
- Medicinal Preparations, and Narcotic Regulations in India
- Drug Advertisement, Animal Ethics, and Drug Price Regulation
- Pharmaceutical Legislation, Ethics, and Legal Rights
Unit II Summary: Anti-Anginal, Diuretics, and Anti-Hypertensives
This unit explains medicines used in heart-related problems. To begin with, anti-anginal drugs help reduce chest pain. For example, vasodilators like Nitroglycerin*, Isosorbide dinitrate*, and Dipyridamole increase blood flow to the heart. Similarly, calcium channel blockers such as Amlodipine, Verapamil, and Diltiazem relax the heart muscles and lower blood pressure.
Next, let’s look at diuretics, which help remove extra water and salt from the body. There are different types. Firstly, carbonic anhydrase inhibitors like Acetazolamide* reduce fluid in the body. Secondly, thiazide diuretics such as Hydrochlorothiazide lower blood pressure effectively. Thirdly, loop diuretics like Furosemide* act fast and are used in emergencies. In contrast, potassium-sparing diuretics like Spironolactone help keep potassium in the body. Finally, osmotic diuretics like Mannitol are used to treat brain swelling.
After that, the unit discusses anti-hypertensive drugs. These are used to manage high blood pressure. Examples include beta-blockers like Timolol, ACE inhibitors like Captopril and Enalapril, and central-acting drugs such as Clonidine* and Methyldopa. Furthermore, vasodilators like Minoxidil and Sodium nitroprusside help relax blood vessels.
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