Pharmaceutical Organic Chemistry

Preparation of Carbonyl compounds Definition Preparation of carbonyl compounds refers to the chemical processes used to synthesize aldehydes and ketones, which are organic compounds containing the carbonyl group (C=O). 1. Oxidation of Alcohols Aldehydes: Primary alcohols can be selectively oxidized to aldehydes using mild oxidizing agents such as pyridinium chlorochromate (PCC) or Dess-Martin periodinane. Ketones: … Read more

Carbonyl compounds Definition Carbonyl compounds are organic compounds that contain a carbonyl group (C=O) as their functional group. The two major classes are: Physical Properties Molecular Structure: The carbonyl group consists of a carbon atom double-bonded to an oxygen atom, creating a site of high electron density. In aldehydes, the carbonyl group is bonded to … Read more

Carbonyl compounds (Aldehydes and ketones) are a significant class of organic compounds, including aldehydes and ketones, characterized by the presence of a carbonyl group (C=O). This group, comprising a carbon atom double bonded to an oxygen atom, contributes to their reactivity and polarity. Aldehydes and ketones play vital roles in various industrial and synthetic applications due … Read more

Propylene Glycol Definition Propylene glycol is a synthetic organic compound with the chemical formula C₃H₈O₂. It is a colorless, odorless, slightly viscous liquid that is hygroscopic (absorbs water) and miscible with water, acetone, and chloroform. Structure: Chemical Formula: C₃H₈O₂ Molecular Structure: Contains a three-carbon chain with two hydroxyl groups (-OH) attached to the first and … Read more

Glycerol (Glycerin) Definition Glycerol, also known as Glycerin (or Glycerine), is a simple polyol compound with the molecular formula C₃H₈O₃. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. It contains three hydroxyl (–OH) groups, which makes it highly hydrophilic (water-attracting) and soluble in water. Structure: Chemical Formula: C₃H₈O₃ Molecular Structure: Consists … Read more

Benzyl Alcohol Definition Benzyl alcohol is an aromatic alcohol with the chemical formula C₆H₅CH₂OH. It consists of a benzene ring (C₆H₅–) attached to a methylene group (–CH₂–), which in turn is bonded to a hydroxyl group (–OH). Structure: Chemical Formula: C₆H₅CH₂OH Molecular Structure: Contains a benzene ring (C₆H₅-) attached to a methanol group (-CH₂OH). Geometry: … Read more

Cetostearyl Alcohol Definition Cetostearyl Alcohol is a white, waxy solid that functions primarily as an emulsifying agent, thickener, and emollient in topical products. It is categorized as a nonionic surfactant and fatty alcohol. Structure: Chemical Formula: A mixture of cetyl alcohol (C₁₆H₃₃OH) and stearyl alcohol (C₁₈H₃₇OH). Molecular Structure: Long-chain fatty alcohols, where cetyl alcohol has … Read more

Chlorobutanol Definition  Chlorobutanol is a trihalogenated alcohol used primarily as a preservative, antiseptic, sedative, and local anesthetic in pharmaceutical formulations. Structure: Chemical Formula: C₄H₇Cl₃O Molecular Structure: Contains a four-carbon chain with three chlorine atoms attached to the first carbon and a hydroxyl group (-OH) on the fourth carbon. Geometry: Tetrahedral around carbon atoms with substituent … Read more

Methyl Alcohol (Methanol) Definition Methyl Alcohol, also known as Methanol, is the simplest alcohol with the chemical formula CH₃OH. It consists of a methyl group (CH₃–) linked to a hydroxyl group (–OH). Structure: Chemical Formula: CH₃OH Molecular Structure: Consists of a single carbon atom bonded to three hydrogen atoms and one hydroxyl group (-OH). Geometry: … Read more

Ethyl Alcohol (Ethanol) Definition Ethyl alcohol, also known as ethanol, is a clear, colorless, volatile, and flammable liquid with the chemical formula C₂H₅OH. It is the type of alcohol found in alcoholic beverages and is also widely used as a solvent, disinfectant, and fuel additive. Structure: Chemical Formula: C₂H₅OH Molecular Structure: Comprises a two-carbon chain … Read more