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Structure and Uses of Important Carboxylic acids

Structure and uses of important Aliphatic amines


Pharmaceutical Organic Chemistry I

Other Subjects of B Pharmacy 2nd Semester

Topic wise notes of:

Pathophysiology

  • Cell injury & Inflammation U-1
  • Cardiovascular, Renal System U-2
  • Respiratory & Urinary system U-3
  • Haematological Diseases U-4
  • Bones Diseases, Cancer U-5

Topic wise notes of:

Biochemistry

  • Nomenclature & Isomerism U-1
  • Conjugate Dienes U-2
  • Alkyl Halides & Alcohols U-3
  • Carbonyl Compounds U-4
  • Carboxylic Acids U-5

Peripheral Nervous System

Topic wise notes of:

Human Anatomy & Physiology II


Carboxylic Acids and Aliphatic Amines – Summary

Unit V focuses on the chemistry of carboxylic acids and aliphatic amines, highlighting their properties, reactivity, and real-world applications. It begins with a detailed discussion on the acidity of carboxylic acids, explaining how the presence of electron-withdrawing or donating substituents affects their acidic strength through the inductive effect. Additionally, the unit covers qualitative tests used to identify carboxylic acids, along with their derivatives, such as amides and esters.

The unit also explores the structure and uses of several important carboxylic acids including acetic acid, lactic acid, tartaric acid, citric acid, succinic acid, oxalic acid, salicylic acid, and benzoic acid. It further includes industrially and pharmaceutically significant compounds such as benzyl benzoate, dimethyl phthalate, methyl salicylate, and acetylsalicylic acid (aspirin), which are widely used in medicines, cosmetics, and food additives.

The second part of the unit focuses on aliphatic amines, discussing their basicity and how substituents influence their basic character. It includes qualitative tests for amine identification and details the structure and uses of key compounds like ethanolamine, ethylenediamine, and amphetamine, which have applications in pharmaceuticals, personal care, and chemical synthesis.

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